Meet the Research Team

Our team is truly interdisciplinary, uniting specialists from nephrology, biomedical engineering, and biology, all driven to end reliance on dialysis. We are close to the dialysis ward, indeed our project leader Dr. Gerritsen, works there. We see the suffering every day. We have real skin in the game to try our hardest to end dialysis.

Our effort bridges across the University Medical Centre Utrecht (UMCU) and the University of Utrecht (UU). At the UMCU we are mainly developing the the blood filtration component of the artificial kidney, the hemofilter device. At the UU we are developing the biology and ascertaining its interraction with artificial substates and how to best obtain function. We have the ambition of bringing these two components together in a clinically meaningful prototype.

Our Team

Karin Gerritsen, MD PhD
Associate professor, Nephrologist
K.G.F. Gerritsen, MD PhD

‘I am dedicated to advancing the implantable artificial kidney to replace dialysis since dialysis is more about surviving than truly living.

I've seen incredibly resilient people who managed to combine the intensive treatment with a relatively normal life, even undergoing pregnancy, or finding peace in a life with many limitations. But I've also seen young people struggle deeply, some losing hope entirely.

Without alternatives like a kidney transplant, this degenerative condition leads to declining health, harmful substance buildup, and overwhelming challenges.

For many, life on dialysis is incredibly difficult, and we must strive to offer better options.’

Roos Masereeuw, Prof. PhD
Professor of pharmacological sciences
Roos Masereeuw

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Fokko Wieringa, PhD ir.
Associate professor, Principle scientist artificial organs IMEC
Fokko Wieringa

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Jeroen Vollenbroek, PhD ir.
Assistant professor
Jeroen Vollenbroek

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Silvia Mihaila, PhD
Assistant professor
Silvia Mihaila

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Ronald van Gaal, PhD
Postdoc researcher
Ronald van Gaal

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Merle Krebber, PhD
Postdoc researcher
Merle Krebber

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Dian Bolhuis, MD.
Clinician researcher
Dian Bolhuis

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Tadeo Alcerreca Valdez, MSc
PhD candidate
Tadeo Alcerreca Valdez

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Tugrul Irmak, PhD ir.
Postdoc researcher
Tugrul Irmak

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João Brás, MSc
PhD candidate
João Brás

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Martijn Ekhart, MSc
PhD candidate
Martijn Ekhart

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Leyla Sharafutdinova, MSc
PhD candidate
Leyla Sharafutdinova

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Working together to solve deep technological problems

Implantable Artificial Kidney

For more than 80 years, dialysis has kept people with kidney failure alive. Now, our team is working on the next big step: an implantable artificial kidney that can truly replace dialysis. Over the last two years, we’ve made significant progress, but with additional researchers, engineers, and resources, we can develop faster. We have real skin in the game to make this happen.

Why We Need Your Support:

Accelerate Research & Development
Our primary goal is to develop a fully implantable artificial kidney that mimics the body’s own filtering and reabsorption processes. Your contribution will help bring on board the talent, technology, and materials we need to push towards a future without dialysis.

Focus on Two Core Components

  • The Hemofilter – An acellular membrane built using nanotechnology that filters waste from the blood.
  • The Bioreactor – Containing kidney epithelial cells to reabsorb essential nutrients and water.

Harness Latest Advances
We believe that leveraging recent developments in membrane science, nanotechnology, and 3D-(bio)printing makes the artificial kidney feasible. With your help, we can speed up development, refine our designs, and continue towards achieving our target of a full-scale artificial kidney by 2031.

Clear Path to Certification
Bringing any medical device to market requires rigorous testing and certification. With your donation, we can scale our small team and navigate these critical steps more efficiently—ultimately bringing this life-changing device to patients sooner.

Schematic diagram of the implantable artificial kidney
A conceptual diagram illustrating the hemofilter and bioreactor.